Rebirth of the God-level Xueba
Chapter 1373: Enzyme replacement
"Uncle, please tell me, Director Yang is here, right? One Reading WWW.W.K.ANSHU.COM" combed through the translation of 37 minutes, came to the door of the ion channel laboratory, with a smiling face, Uncle Qin, the concierge handed a cigarette.
Uncle Qin took it unceremoniously, took a look, and found that it was all in English, so he put it in his mouth, and said vaguely: "The conditions are good, you can afford to smoke outside."
The translator quickly lit the cigarette for him, and said with a smile: "To do things for foreign companies, you have to decorate it."
"Well, the taste is heavy enough, and it has the power of a smoky pot." Uncle Qin commented.
The interpreter twitched the corners of his mouth twice, and said in his heart: If you want to smoke, I said earlier, I will weigh you a catty of loose cigarettes.
Uncle Qin inhaled one third of the roots in one breath, spit it out, nodded comfortably, and then said: "Which unit are you from? What can I do with Director Yang? Have you made an appointment?"
Uncle Qin opened the registration book while asking the question, pushed it to the translator, and said: "Foreigners also need to see their documents. We are a confidential unit here, you know."
"I know." The translator glanced at the police booth next to him. There were also armed police soldiers who did not know when they came. He also asked a little faintly: "In our ion channel laboratory, when has an armed police stand guard?"
"To make new medicines, it's the same amount of money as the sea, can it be done without sending an armed police?" Uncle Qin took it for granted.
In terms of the value of new drugs, the cost and profit of tens of millions of dollars at every turn is indeed higher than that of most domestic state-owned enterprises. Sending an armed police to stand guard is not exceptional. However, being able to make changes so quickly is not an exception. The translation does not understand.
Fortunately, the foreigner didn’t understand. The translator filled out the registration book and smiled back at the customer: “Mr. Liander, the ion channel laboratory of Peking University is a government-invested laboratory. They only send police officers to ensure its safety. Restricting the entry and exit of foreigners will not affect your residence in China."
"Are you sure?" Liander is a white-haired, yellow-haired foreigner. His eyebrows stretched out an inch from his forehead, and he was trimmed very carefully.
"I'm sure." The translator gritted his teeth and gave an answer, fearing that the foreigner would turn his back on his voice, and then said busy: "Director Yang is in the laboratory now, I just registered, but we are ranked sixth today, no I will definitely be able to see it. I have to call to confirm in a while, or I will take you to play for an afternoon and come back tomorrow?"
"Mr. Yang Rui must be very busy now, you can confirm with them that I really want to cooperate, maybe I can meet in advance." Liandel speaks as slowly as possible so that the translator can understand what he is saying.
The interpreter was taken aback for a moment and smiled: "Okay, then I'll discuss it again, but people said that there is no time today. Director Yang will not receive guests today. ?W?W?W?·K?A书NSCU ·COM"
Liandel nodded silently.
The translation is a bit weird, but I feel a little proud of it inexplicably. In the past, although it was easy to pit foreigners for money, they were called around and drunk after all. To arrange travel or something, you must endure unreasonable interpretations of Chinese culture and history by foreigners. Now, although I am a little begging for help, foreigners are begging for it. Chinese, he is just a middleman, but he feels excited.
asked two more specific sentences, translated to the front of the concierge, muttered for a long time, turned around, and asked Liandre: "Would you like to see Yang Rui with other people?"
"See you together?"
"I said that you are the manager of a pharmaceutical company, and the other party said that if you are willing to work with the manager of another pharmaceutical company, you can advance it, otherwise, you have to wait."
Li Ander looked at the concierge Uncle Qin suspiciously, and asked, "Does he have such a right to make this decision?"
"Maybe it was decided long ago in the ion channel laboratory."
"Well, if we meet together, can I see Yang Rui today?"
The translator shook his head slightly and said, "It can only be tomorrow afternoon. Or, I will take you to the Forbidden City to take a look. There are many Chinese antiques and cultural relics in it."
"What would Mr. Yang Rui like? Let's go buy something he likes." Liandel said purposefully.
The translator opened his mouth, nodded, and said, "Then go to the Friendship Store."
Afternoon the next day.
Liandel had a simple lunch and brought canned food and malted milk extract from the Friendship Store to the ion channel laboratory.
From personal experience, Liandel did not believe that Yang Rui would like canned food and malted milk extract. However, the translation said that this was a high-end gift that Chinese people gave each other, and Liandel believed it. After all, which country do people have no hobbies?
Yang Rui was in the living room and felt a little dazed when he received a gift from Liandre. There are foreigners who try to bribe these days, but what about using canned food and malted milk? The ones bought in the Friendship Store are not suitable either.
"Mr. Leander, please wait a moment." Yang Rui could only put the canned food and malted milk extract on the table, and told the scientific research dog who helped in the conference room to bring it back to the foreigner later.
Li Andel was very happy, thinking that Yang Rui had accepted his gift, and asked boldly: "Professor Yang, what other pharmaceutical companies will participate in the talks?"
"Greenstone Point, Grunskas, and Zelecom are sure to participate. I'm not sure if the others will come." Yang Rui said a few names casually.
Liandel immediately felt the threat of the advent of the enemy.
Compared to the Karitz Pharmaceuticals company where he works, both Zeleca and Glasgow can be said to be behemoths.
Liander had no chance to speak, just raising his hand to look at his watch, several men with blond, brown or white hair walked in.
Yang Rui looked a little funny. Europeans and Americans have not yet begun to play with diversity. Therefore, on both sides of the conference table today, sitting on both sides of the conference table are all white men, not to mention that there are no people of color, not even women.
The pharmaceutical companies in the 1980s were pure patriarchal politics. Otherwise, there would be no organized public relations projects for women.
Yang Rui thought so arrogantly, and then waited for everyone to sit together, and said: "Everyone's time is precious, I'll just say it straightforwardly."
He uses Chinese, and he has his own interpreter next to it to worry about how to translate it straightforwardly.
After the latter had spoken in English, Yang Rui said again: "Everyone who came to the ion channel laboratory today are all interested in the medicines in this laboratory. Taking into account the professionalism of medicines, I have prepared some brochures for everyone. Look. Well, after reading it, please return the brochure."
After , some people began to distribute black-and-white printed paper products.
"Gauchier's disease?" Liandel opened the pamphlet and saw this proper term.
"Yes, glucocerebrosidosis. According to the classification of Europe and the United States, this is a rare disease. The current number of patients in the world is not very large, roughly in the hundreds of thousands." Yang Rui After a pause, he said: "Therefore, in order to balance expenses, the partner I need should be a company that has the ability to apply for rare diseases, preferably a company with rare disease sales experience..."
Yang Rui babbled hundreds of words before letting the translator speak.
Several company representatives did not pay much attention to this aspect.
Large pharmaceutical companies have hands and eyes, even if it is transnational politics, let alone the compliance application of the old family.
Their real concern is still whether Yang Rui can make a new medicine.
"Which plan do you want to use to develop drugs for Gaucher's disease, and what is the current progress?" The manager of Glensburgh put on his glasses and dragged it lightly, somewhat shrewd.
"Enzyme substitution method." Yang Rui answered without hesitation.
Gaucher disease is a disease caused by genetic mutations. In the final analysis, it is a lack of glucocerebrosidase. Because the structure of the glucocerebrosidase in the patient's body has changed and cannot perform its due function, the human body has a series of symptoms, such as splenomegaly, anemia, bone disease, and nervous system disorders.
Theoretically, supplementation of a sufficient amount of glucosidase can improve the symptoms of patients with this disease.
However, this is obviously not an easy task. At this time, rb enzyme has no effect at all.
The manager of GLENSTK also looked at Yang Rui with suspicion, and asked: "The enzyme substitution method is said to be extremely costly. Can it be used for pharmaceutical-grade production?"
"It's good to reduce costs. In this regard, I am still very confident."
Yang Rui's expression is also full of confidence.
The development of new drugs is no longer unfamiliar to Yang Rui.
To put it bluntly, no more than 200 scientific research units from all over the world can have the level of proficiency of Yang Rui.
is so affirmative because there are not 200 real new drugs developed by the people who are still alive in the world.
Don’t see that in the 1990s, there were more than 4,000 new medicines developed in the entire Western world, or the whole world, but the real new medicine is to use a brand-new compound instead of the isomers of the old compound. The total number of completed new drugs is more than 100.
Deferiprone is one of them.
Although Yang Rui did not operate the whole process until the market of desferiprone, but after the second phase of the clinical trial, the developer can actually do not much. Unless cheating is required, the new drugs from the third phase are basically outsourced. Specialized companies are going to do clinical trials~lightnovelpub.net~ There are tens of thousands of clinical patients at every turn, and clinicians are needed, not drug developers. At this time, developers can’t modify the composition of the active substance. , In fact, it can only be resigned to fate.
After a fateful decision, Deferipone has already completed the development of a new drug so easily that it was launched on the market, without many iterations. Such results, to be honest, shocked some analysts.
Now, with the bonus of the Nobel Prize, Yang Rui’s success is a little taken for granted. The news that Peking University’s ion channel laboratory is trial-produced new drugs has attracted so many pharmaceutical companies all of a sudden.
However, it’s one thing for pharmaceutical companies to be interested, and it’s another thing for investment or cooperation. Liandre took another look at the manager of GLENSTK, hoping that he could ask Yang Rui further to get more information. Good judgment.
The manager of Glenske really pondered for a few seconds, then looked up again, and said: "We at Glenske are willing to invest $1 million to obtain a 10% interest in the future of the drug. Is this okay?"
Liander's chin almost fell off when he heard it, so he would give me money? Are you wealthy enough?
Liandel hurriedly looked at the others, only to see the manager of Greenstone Point, Shi Shiran said: "1.5 million U.S. dollars, 10% equity!"
In just one round of bidding, the price of a new drug that Yang Rui has not yet started has been raised by 5 million US dollars.
Li Ander was dumbfounded, aren't you afraid of being scammed by Yang Rui?