Because of time constraints and heavy tasks, the building of the Clinical Experiment Center of Hedong University used the existing Faculty of Science building.

This building was originally intended for teaching students in the Faculty of Science, and part of it was used as classrooms for teachers. Now it is occupied...Everyone is actually very happy.

After all, a new project has landed. For all the teachers and students of Hedong University, Yang Rui's clinical laboratory center is located in this school, no matter how you look at it, it is a great thing, especially the teachers and students who are studying, they are extremely looking forward to this.

The current distribution system determines that the quality of education is more important than the quality of education.

A good school will have a good unit to ask for people, and a bad school will have a very pure working relationship. Occasionally there will be some omissions. However, for the vast majority of students, it is The school wins glory, it really serves everyone.

The school’s compulsion is not enough, and other people’s units will not come to recruit people at all. How about your quality and your current genius? Would the leaders of government units and state-owned enterprises care?

A provincial-owned enterprise would be very proud that it had snatched a student from Peking University and two students from Beijing University of Technology this year, but it would be very shy to say that we have solved the work of the 12 secondary technical school students in this unit. Of course, it is very rigorous. Solved under the review system...

Even after entering the unit, the university where the first degree is located will still be mentioned on different occasions, which will play a big role from time to time. Especially in vertical systems, such as electricity, post, telecommunications, taxation, railways, water conservancy and other departments, at the provincial, municipal and national levels, there is basically a mainstream school preference, and there will be different changes in different periods of the top leaders. , But it is a reality.

For example, the first and only clinical trial center in the country is located in Hedong University. All the biology, zoology and pharmacy-related enterprises and institutions in the country will definitely pay more attention to Hedong University when selecting candidates this year.

Even hospitals, health bureaus, and other system units, when they select people, they will look up at the students of Hedong University.

The so-called edification, vinegar smoked, and Nobel Prize winner smoked, should have different treatment.

For the students of Hedong University, a building of the Faculty of Science is really not so attractive.

Not to mention, the construction is still stepping up next to it to build a new building.

The excitement of students and faculty members can also prove from another angle that everyone is actively applying to join the clinical trials.

The most taboo of clinical trials not for subsidizing two cents a meal for a few days is to use money to entice people to participate in the experiment. This is different from ordinary people's thinking.

That is, the first phase of the clinical trial, the subsidy is slightly more, because healthy people are used for safety testing, but it is just a little more, which is far from enough to attract people to actively participate in pharmaceutical companies in Europe and the United States in disguise. Give some medical insurance for a longer period of time, so as to have a certain attraction to low-income groups, but the gray area will end here, and further, it is basically illegal parts. Once discovered, the experimental results will be Suspected.

The students, faculty and staff of Hedong University are not because of subsidies and non-existent medical insurance. Their enthusiasm, in the final analysis, can be attributed to their dedication.

In other words, it is a kind of hero complex.

In this era, heroes are still the pursuit of most people, at least, the deep-seated pursuit of most people.

The students, faculty and staff in the ivory tower have this tradition even more.

The experiment was repeated in the first phase, so it went quite well.

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br/> It originally only requires dozens of people to participate. The core of concern is safety and pharmacokinetics. Simply put, what is excreted, will it generate additional toxic clouds in the body? The trouble is to recruit volunteers, analyze and do it by pulling a few skilled experiment dogs, not to mention that Pfizer has already completed the first phase of clinical trials.

Yang Rui's repeated experiments were mainly for verification, so that Pfizer would not deliberately deceive and even buy fakes.

Asking for a good start and familiarizing everyone with the equipment is one of the effects, and you don’t even need to follow the steps of the first phase. If you apply for a license in any country, you don’t need to do the first phase of the clinical trial twice. If you do it for one to five to ten, you don’t have to say anything else, it’s less wasteful to waste millions.

After a short process, the high-profile Phase II clinical trial was on the table.

This time, the building of the clinical experiment center was fully utilized.

The focus of the second phase of clinical trials is divided into two, the first focus is still safety, what to do in the first phase, not only to do in the second phase, but also to expand the scale.

The second concern is the efficacy.

From compound screening to animal experiments, to the first phase of clinical trials, and then to the second phase of clinical trials, the previous part is concerned with curative effects, but none of them have been tested on humans. Now, it’s finally time to get the results. It's time.

Huang Mao made a special trip from Huarui Laboratory for this purpose and was responsible for the overall planning of the experimental work.

Tu Xian and his wife Wang Xiaoyun also traveled to Pingjiang to help. Sildenafil was a drug bought in the name of Yang Rui, and its rights and debts belonged to Yang Rui. Naturally, he could not let the ion channel laboratory or Yang Rui’s genetic engineer. Come and help. In fact, you can go to them to help, but Yang Rui doesn't think it is necessary.

Doctors are most needed in the clinical laboratory center. It does not even need a permanent research team. Whoever wants to test drugs can rent the laboratory center. Changing a research team does not affect the accuracy of the experiment.

Of course, to be on the safe side, the newly-built clinical experiment center of Hedong University still needs a permanent team. Yang Rui entrusted Li Zhangzhen to hire a few doctors and recruited a few pharmacokinetic scholars himself, even if it constitutes the research of the clinical experiment center. team.

That is to say, he is now very prestigious, otherwise, investors will be furious when they see him doing this.

How can I organize the research team after spending all the money, and organize it so casually.

The other one is because of Yang Rui's lack of confidence.

If you don’t have enough confidence, don’t buy sildenafil. How expensive is this?

It really doesn't hurt to sell Ye Tian.

The bank cadres of the four major banks are all distressed.

Yang Rui still directs everyone to do things with a flat attitude.

Said it was a command, but in fact it was also discussed.

He has never done clinical trials before, but a few pharmacokinetic scholars, at least all have experience in the development of proprietary Chinese medicines, combined with some public information, but they have learned decently.

The difficulty of clinical trials is basically the same.

There are many clinical trial centers in Africa in later generations, such as Uganda, and how many qualified doctors can there be.

People make anti-malarial drugs, HIV drugs, and the like, and they still do things like that.

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Rebirth of the God-level Xueba (Zhiniao Village) 00 novel netizens please remind: Please pay attention to the rest of your eyes when reading for a long time. Recommended reading for 00 novels: The Supreme King is too cruel

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However, this is too trivial in the eyes of the banks.

The vice president who came to inspect heard about Yang Rui's fame, and was reluctant to offend him easily, so he directed the manager under him to inquire.

"What are the standards for Phase II clinical trials?"

"What do you estimate its ability to reduce blood pressure?"

"How sure are we to pass the Phase II clinical trial?"

The manager has a lot of questions, but few can get Yang Rui's answer.

Several bank vice presidents had no choice but to look at the snow-white ward every day, as well as the large blackboards full of words in the meeting room.

They couldn't understand the things on the blackboard.

They still couldn't understand the things in the ward.

It's useless to understand it, or it's nothing more than annoying.

Through discussions after dinner, several people have basically made it clear that Yang Rui is suspected of defrauding money, but it is still unclear why he did this.

"Professor Yang, how are the results today?" It was another dusk, Wang Xiaoshu from ICBC, chasing Yang Rui's pace to go out, two-phase exhausted.

"Oh, today's results are not very good either." Yang Rui smiled slightly and showed it to people who didn't know, only if he was calm and had super stress resistance.

Wang Xiaoshu was not in the mood to watch and laugh today. He smiled blankly and said: "The result is still not good, are you not in a hurry? Also, the hundreds of millions of dollars in expenses are not your money."

"Why is it not my money?" Yang Rui became unhappy, and said: "Your bank took out a loan, but it was not given to me. Why? Do you want to erase my debt?"

"I guess that's it!" Wang Xiaoshu jumped up suddenly, not flexible like a 60-year-old veteran cadre, screaming, and said: "You want to use our money for medical development, you are too ruthless. Do you know what is the concept of 180 million US dollars? How much money is that people’s hard-earned money, you just robbed it... I, I am also a person who is about to retire, I am not afraid of you, I want to report to the above and stop this!"

"Stop?" Yang Rui shook his head and said, "Don't be kidding, you are the bank that pays the money. Pharmaceutical development is not your specialty."

"Pharmaceutical development is always Pfizer's specialty, I don't believe that Pfizer did not do the second phase of the clinical trial. They must secretly do the second phase, and they did not perform well before selling it to you. I don't understand pharmaceutical development, but I do. Buying transactions, fools sell you drugs like this, a big deal of hundreds of millions of dollars, can it be so casual? That is to say, you young people dare to do it like this."

What Wang Xiaoshu said surprised Yang Rui.

It is very interesting to say that Pfizer might steal the second phase of the clinical trial.

Unlike many Chinese nowadays, foreigners feel that foreigners are very obedient.

Pharmaceutical companies are in the business of life, well, follow your sister's rules.

It is indeed difficult to secretly conduct clinical trials, but it is difficult not to say that it cannot be done.

It is true that Pfizer cannot openly conduct Phase II clinical trials, but it is still possible to conduct a small-scale efficacy study in private.

Of course, this kind of small-scale testing often fails to fully grasp the status of the drug, and it is likely that omissions may occur. However, Pfizer made up for the omissions with expensive contracts.

and so,

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Rebirth of the God-level Xueba (Zhiniao Village) 00 novel netizens please remind: Please pay attention to the rest of your eyes when reading for a long time. Recommended reading for 00 novels: The Supreme King is too cruel

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Although Yang Rui does not know whether Pfizer has done clinical phase II, Wang Xiaoshu's guess is quite reasonable.

It is likely that Pfizer did not see good results in a small-scale test before it decided to sell sildenafil to Yang Rui.

At the very least, they did certain tests and judgments before selling them.

As far as the blood pressure reduction effect is concerned, Pfizer’s reasons for selling sildenafil are already abundant.

Wang Xiaoshu's guess is also very reasonable.

Unfortunately, he does not have the right to decide.

Yang Rui said: "I can't explain to you scientific research. Obviously you don't know much about the medical field. In short, what you think is your business, believe it or not, I can't control it, but if you influence my research , I'm welcome."

"It's useless if you are not polite to me. I know you are Professor Yang Tang, but I tell you that the four funding banks have already negotiated. If you don't give a reasonable explanation, we will deal with it if necessary. Next, freeze your money." Wang Xiaoshu seems to be aggressive, but in fact he is still very guilty. To say that his level is already very high, let alone a small research institute, even the central enterprises dare not despise him.

However, when speaking, Comrade Wang Xiaoshu still gave enough retreat. While winning over the other three banks, he said that it was a reasonable explanation. When necessary...

Yang Rui looked behind him, shook his head, and said, "Where are the representatives of the other three banks?"

"It's okay for me." Wang Xiaoshu was also a little embarrassed. Among the four, UU read www. uukanshu. Com is the oldest, the closest to retirement, and the strongest sense of justice. The attitude of other people, it should be said that there is no two things, behind the tacit consent, it is not certain how it will be in person.

Yang Rui guessed the reason, and smiled disdainfully: "Let me say that."

"I'm listening." Wang Xiaoshu concentrated.

Yang Rui gave an "en" and raised his voice slightly to ensure that he could hear people hiding around him: "Which bank is the first to find trouble, the debt of which bank will be paid off finally, listen clearly. ?"

Regardless of whether it is 180 million or 580 million U.S. dollars, the four banks all contribute proportionally, but when it comes to repayment, can it return hundreds of millions of dollars in one go?

Of course it is impossible. Even if the new drug is sold in one go, the other party may pay in batches, and maybe they will use shares to deduct cash or something. Not to mention the sales return, it is always going to happen one after another.

If you can’t sell it, it’s even worse. If you don’t have enough money for repayment, who should you give first and then whom?

If it is implemented in accordance with the law, the debt repayment is always in order.

However, no matter how strict the law is, there is room for action, let alone the non-standard debts of the Big Four and Yang Rui.

When it comes time to give the money, Yang Rui does not give the money proportionally, or pays the money in order. Who can do it?

Wang Xiaoshu seemed to have been hit in the chest by a heavy hammer, and his blood pressure was so high in an instant.

"Okay, go back and take a good rest. Tomorrow I will take you to see the specific situation and let you know more about the clinical experiment." Yang Rui was also afraid of angering the veteran cadres. He eased the scene with a smile and gave Wang Xiaoshu a step down.

"I want to bring an expert." Wang Xiaoshu blushed and took the opportunity to make a request.

"No problem." Yang Rui nodded and agreed. He was confident about the effect of sildenafil on lowering blood pressure... the result should be quite stable.